1. Gene Therapy Products

Engensis(VM202)

Engensis (VM202) is an innovative gene therapy
drug that provides fundamental treatment through
tissue regeneration.​

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Claudication​

Claudication is pain in the thigh, calf, or buttocks that happens during walking. It can be a symptom of peripheral artery disease (PAD). This is when narrowed or blocked arteries reduce the blood flow to the legs.​

At first, claudication pain occurs when walking a certain distance and goes away when resting. But as the disease gets worse, the pain can occur when walking shorter distances. Over time, walking may not be possible because the pain is so severe.​

Peripheral artery disease (PAD) is very common, mainly in people over age 50. PAD is caused by narrowed or blocked arteries in the legs or in the body’s main artery (the aorta). This can reduce blood flow to muscles in the calf, thigh, or buttocks. This decreased blood flow may cause the pain that leads to claudication. ​

Current treatment includes medication and surgical procedures such as angioplasty or bypass. These treatment have limitations and will not regenerate vascular tissue damaged from reduced blood flow.

Main symptoms​

  • Cyanosis

  • Stabbing pain​

Status of clinical trials

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Indication Pre-clinical Phase 1 Phase 2 Phase 3
Claudication​